Contents
What Is Cri du Chat Syndrome?
Cri du Chat Syndrome (CdCS) is a rare genetic disorder caused by a partial deletion of the short arm of chromosome 5. This disorder is characterized by a high-pitched cry resembling that of a cat in infancy and a wide range of mild to moderate physical, mental and behavioral issues. Common symptoms associated with CdCS include delayed development, intellectual disability, speech difficulty, distinctive facial features, and varying degrees of mobility issues.
Causes of Cri du Chat Syndrome
Cri du Chat Syndrome is a genetic disorder caused by a partial deletion of the short arm of chromosome 5. Although the exact cause of the chromosome deletion is unknown, it is believed to be the result of a recombination event during meiosis, which is the process of cells dividing in order to reproduce.
Symptoms of Cri du Chat Syndrome
Common symptoms of CdCS include a characteristic cat-like cry in infancy, delayed development, intellectual disability, and distinctive facial features. Other symptoms associated with CdCS can include microcephaly, weak muscle tone, gastroesophageal reflux, and hearing loss.
Treatment and Health Considerations for Cri du Chat Syndrome
The treatment for CdCS is largely symptomatic, and may include physical therapy, speech therapy, occupational therapy and/or educational interventions. Treatment is highly individualized, and may also include in-home sensory stimulation and adaptive behavior strategies. Additionally, children with CdCS may benefit from mental health services, support and advocacy.
Keywords:
Cri du Chat Syndrome, Chromosome Deletion, Delayed Development, Intellectual Disability, Physical Therapy, Speech Therapy, Mental Health Services.